Anti-PIAS2 Polyclonal Antibody
品牌:solarbio | 货号:K004110P
英文名称 |
Anti-PIAS2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ARIP3;DIP;MIZ;MIZ1;PIASX;PIASX-ALPHA;PIASX-BETA;SIZ2;ZMIZ4 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
68kDa |
Gene ID |
9063 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PIAS2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PIAS2 |
Subcellular Locations |
Nucleus Nucleus speckle PML body |
Swiss Prot |
O75928 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. |