Anti-GABRA1 Polyclonal Antibody
品牌:solarbio | 货号:K007712P
英文名称 |
Anti-GABRA1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
EJM;ECA4;EJM5 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:25-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
52kDa |
Gene ID |
2554 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human GABRA1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human GABRA1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P14867 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene |