Anti-PGLYRP1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PGLYRP1 Polyclonal Antibody

品牌:solarbio | 货号:K007794P

英文名称 Anti-PGLYRP1 Polyclonal Antibody
宿主 Rabbit
别名 PGRP;TAG7;PGRPS;PGLYRP;PGRP-S;TNFSF3L
应用 WB
稀释比例 WB 1:200-1000.
交叉反应 Human Mouse Rat
蛋白分子量 22kDa
Gene ID 8993
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human PGLYRP1
性状 液体
Public Immunogen Range A synthetic peptide of human PGLYRP1
Swiss Prot O75594
克隆类型 Polyclonal Antibody
背景资料 Peptidoglycan recognition proteins (PGRPs) are molecules that recognize peptidoglycan, a large component in bacterial cell walls. In insects, PGRPs activate antimicrobial pathways, and in mammals PGRPs function as antibacterial neutrophil proteins. PGRP-L halts bacterial growth by acting as an alanine amidase, an enzyme that hydrolyzes the amide bond of bacterial peptidoglycan. PGRP-I? and PGRP-I∫ are also members of the PGRP family that help recognize bacteria by binding to peptidoglycan and Gram-positive bacteria, but they do not have amidase activity. PGRP-S participates in intracellular killing of Gram-positive bacteria by stimulating two antimicrobial defense systems, the prophenoloxidase cascade and the antimicrobial peptides through Toll receptors.