Anti-SASH1 Polyclonal Antibody
品牌：solarbio | 货号：K007820P
| 英文名称 | Anti-SASH1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SH3D6A;dJ323M4.1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:30-150. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 137kDa |
| Gene ID | 23328 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human SASH1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human SASH1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | O94885 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. |