Anti-DCX Polyclonal Antibody
品牌:solarbio | 货号:K007925P
英文名称 |
Anti-DCX Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
DC;DBCN;LISX;SCLH;XLIS |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:25-100. |
交叉反应 |
Human |
蛋白分子量 |
49kDa |
Gene ID |
1641 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human DCX |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human DCX |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
O43602 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. |