Anti-CASP4 Polyclonal Antibody
品牌：solarbio | 货号：K007971P
| 英文名称 | Anti-CASP4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | TX;Mih1;ICH-2;Mih1/TX;ICEREL-II;ICE(rel)II |
| 应用 | IHC |
| 稀释比例 | IHC 1:30-150. |
| 交叉反应 | Human |
| 蛋白分子量 | 43/37/13/30/18kDa |
| Gene ID | 837 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CASP4 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CASP4 |
| Subcellular Locations | Cytoplasm Membrane |
| Swiss Prot | P49662 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. |