Anti-XRN1 Polyclonal Antibody
品牌：solarbio | 货号：K007973P
| 英文名称 | Anti-XRN1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SEP1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:10-50. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 194kDa |
| Gene ID | 54464 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human XRN1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human XRN1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q8IZH2 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the 5′-3′ exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. |