Anti-CD163 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CD163 Polyclonal Antibody

品牌:solarbio | 货号:K005801P

英文名称 Anti-CD163 Polyclonal Antibody
宿主 Rabbit
别名 M130;MM130;SCARI1
应用 WB
稀释比例 WB 1:500-1000.
交叉反应 Human Mouse Rat
蛋白分子量 125kDa
Gene ID 9332
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CD163
性状 液体
Public Immunogen Range Recombinant protein of human CD163
Subcellular Locations Cell membrane Secreted Single-pass type I membrane protein
Swiss Prot Q86VB7
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.