Anti-CD163 Polyclonal Antibody
品牌:solarbio | 货号:K005801P
英文名称 |
Anti-CD163 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
M130;MM130;SCARI1 |
应用 |
WB |
稀释比例 |
WB 1:500-1000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
125kDa |
Gene ID |
9332 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CD163 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CD163 |
Subcellular Locations |
Cell membrane Secreted Single-pass type I membrane protein |
Swiss Prot |
Q86VB7 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |