Anti-ALAD Polyclonal Antibody
品牌：solarbio | 货号：K005808P
| 英文名称 | Anti-ALAD Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ALADH;PBGS |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 36kDa |
| Gene ID | 210 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ALAD |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ALAD |
| Subcellular Locations | Cytosol Nucleus secreted |
| Swiss Prot | P13716 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. |