Anti-AUP1 Polyclonal Antibody
品牌:solarbio | 货号:K008303P
| 英文名称 | Anti-AUP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Ancient ubiquitous protein 1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 53kDa |
| Gene ID | 550 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human AUP1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human AUP1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q9Y679 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25. |