Anti-B Raf Polyclonal Antibody
品牌：solarbio | 货号：K008370P
| 英文名称 | Anti-B Raf Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NS7;BRAF1;RAFB1;B-RAF1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 84kDa |
| Gene ID | 673 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human BRAF |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human BRAF |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P15056 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. |