Anti-BMP2 Polyclonal Antibody
品牌:solarbio | 货号:K101544P
英文名称 |
Anti-BMP2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ACAA;PTHIO;THIO;BMP-2A;BDA2 |
应用 |
WB |
稀释比例 |
WB 1:3000. |
交叉反应 |
Mouse |
蛋白分子量 |
45kDa |
Gene ID |
12156 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human BMP2 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human BMP2 |
Subcellular Locations |
secreted |
Swiss Prot |
P21274 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4. |