Anti-CREB3 Polyclonal Antibody
品牌：solarbio | 货号：K004621P
| 英文名称 | Anti-CREB3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | LUMAN;LZIP;sLZIP |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:10-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 44kDa |
| Gene ID | 10488 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CREB3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CREB3 |
| Subcellular Locations | Cytoplasm Endoplasmic reticulum membrane Membrane Nucleus Single-pass type II membrane protein |
| Swiss Prot | O43889 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined. |