Anti-H2AFZ Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-H2AFZ Polyclonal Antibody

品牌:solarbio | 货号:K004657P

英文名称 Anti-H2AFZ Polyclonal Antibody
宿主 Rabbit
别名 H2A.Z-1;H2A.z;H2A/z;H2AZ
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 14kDa
Gene ID 3015
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human H2AFZ
性状 液体
Public Immunogen Range Recombinant protein of human H2AFZ
Subcellular Locations Chromosome Nucleus
Swiss Prot P0C0S5
克隆类型 Polyclonal Antibody
背景资料 Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.