Anti-H2AFZ Polyclonal Antibody
品牌:solarbio | 货号:K004657P
英文名称 |
Anti-H2AFZ Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
H2A.Z-1;H2A.z;H2A/z;H2AZ |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
14kDa |
Gene ID |
3015 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human H2AFZ |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human H2AFZ |
Subcellular Locations |
Chromosome Nucleus |
Swiss Prot |
P0C0S5 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. |