Anti-TAF5 Polyclonal Antibody
品牌：solarbio | 货号：K005097P
| 英文名称 | Anti-TAF5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | TAF(II)100;TAF2D;TAFII-100;TAFII100 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 87kDa |
| Gene ID | 6877 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TAF5 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TAF5 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q15542 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex. This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex. Alternative splicing results in multiple transcript variants. |