Anti-TEK Polyclonal Antibody
品牌：solarbio | 货号：K005098P
| 英文名称 | Anti-TEK Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD202B;GLC3E;TIE-2;TIE2;VMCM;VMCM1 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 126kDa |
| Gene ID | 7010 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TEK |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TEK |
| Subcellular Locations | Cell junction Cell membrane Cytoplasm Secreted Single-pass type I membrane protein cytoskeleton focal adhesion |
| Swiss Prot | Q02763 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. |