Anti-CXCL11 Polyclonal Antibody
品牌：solarbio | 货号：K004364P
| 英文名称 | Anti-CXCL11 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | H174;I-TAC;IP-9;IP9;SCYB11;SCYB9B;b-R1 |
| 应用 | IHC |
| 稀释比例 | IHC 1:100-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 10kDa |
| Gene ID | 6373 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CXCL11 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CXCL11 |
| Subcellular Locations | Secreted |
| Swiss Prot | O14625 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. |