Anti-DCN Polyclonal Antibody
品牌:solarbio | 货号:K007444P
英文名称 |
Anti-DCN Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CSCD;PG40;PGII;PGS2;DSPG2;SLRR1B |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:50-300. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
40kDa |
Gene ID |
1634 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human DCN |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human DCN |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P07585 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. |