Anti-HSD11B1 Polyclonal Antibody
品牌：solarbio | 货号：K007448P
| 英文名称 | Anti-HSD11B1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HDL;11-DH;HSD11;HSD11B;HSD11L;CORTRD2;SDR26C1;11-beta-HSD1 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 32kDa |
| Gene ID | 3290 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human HSD11B1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human HSD11B1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P28845 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein. |