Anti-TRAF3 Polyclonal Antibody
品牌:solarbio | 货号:K003586P
英文名称 |
Anti-TRAF3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CAP-1;CAP1;CD40bp;CRAF1;IIAE5;LAP1 |
应用 |
WB IHC IF IP |
稀释比例 |
WB 1:200-1000. IHC 1:50-200. IF 1:50-200. IP 1:50-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
64kDa |
Gene ID |
7187 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human TRAF3 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human TRAF3 |
Subcellular Locations |
Cytoplasm Endosome Mitochondrion |
Swiss Prot |
Q13114 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. |