Anti-TRAF3 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-TRAF3 Polyclonal Antibody

品牌:solarbio | 货号:K003586P

英文名称 Anti-TRAF3 Polyclonal Antibody
宿主 Rabbit
别名 CAP-1;CAP1;CD40bp;CRAF1;IIAE5;LAP1
应用 WB IHC IF IP
稀释比例 WB 1:200-1000. IHC 1:50-200. IF 1:50-200. IP 1:50-100.
交叉反应 Human Mouse
蛋白分子量 64kDa
Gene ID 7187
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human TRAF3
性状 液体
Public Immunogen Range A synthetic peptide of human TRAF3
Subcellular Locations Cytoplasm Endosome Mitochondrion
Swiss Prot Q13114
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.