Anti-NFASC Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-NFASC Polyclonal Antibody

品牌:solarbio | 货号:K003571P

英文名称 Anti-NFASC Polyclonal Antibody
宿主 Rabbit
别名 NF;NRCAML
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量 150kDa
Gene ID 23114
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human NFASC
性状 液体
Public Immunogen Range Recombinant protein of human NFASC
Subcellular Locations Plasma membrane
Swiss Prot O94856
克隆类型 Polyclonal Antibody
背景资料 This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.