Anti-NFASC Polyclonal Antibody
品牌：solarbio | 货号：K003571P
| 英文名称 | Anti-NFASC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NF;NRCAML |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 150kDa |
| Gene ID | 23114 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NFASC |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NFASC |
| Subcellular Locations | Plasma membrane |
| Swiss Prot | O94856 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined. |