Anti-TRAF4 Polyclonal Antibody
品牌：solarbio | 货号：K006845P
| 英文名称 | Anti-TRAF4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CART1;MLN62;RNF83 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 54kDa |
| Gene ID | 9618 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TRAF4 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TRAF4 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9BUZ4 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. |