Anti-alpha-Synuclein Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-alpha-Synuclein Polyclonal Antibody

品牌:solarbio | 货号:K106539P

英文名称 Anti-alpha-Synuclein Polyclonal Antibody
宿主 Rabbit
别名 NACP;PARK1;PARK4;PD1
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 17kDa
Gene ID 6622
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human alpha-Synuclein
性状 液体
Public Immunogen Range A synthetic peptide of human alpha-Synuclein
Subcellular Locations Cell junction Cytoplasm Membrane Nucleus Secreted cytosol synapse
Swiss Prot P48061
克隆类型 Polyclonal Antibody
背景资料 Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer’s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.