Anti-PAK7 Polyclonal Antibody
品牌：solarbio | 货号：K008216P
| 英文名称 | Anti-PAK7 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PAK5 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:15-50. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 81kDa |
| Gene ID | 57144 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PAK7 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PAK7 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9P286 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. |