Anti-DKK2 Polyclonal Antibody
品牌:solarbio | 货号:K008141P
英文名称 |
Anti-DKK2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
DKK-2 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
28kDa |
Gene ID |
27123 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human DKK2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human DKK2 |
Swiss Prot |
Q9UBU2 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). |