Anti-EIF4EBP1 Polyclonal Antibody
品牌：solarbio | 货号：K008094P
| 英文名称 | Anti-EIF4EBP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BP-1;4EBP1;4E-BP1;PHAS-I |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 13kDa |
| Gene ID | 1978 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human EIF4EBP1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human EIF4EBP1 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q13541 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. |