Anti-APIP Polyclonal Antibody
品牌：solarbio | 货号：K008086P
| 英文名称 | Anti-APIP Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | APIP2;CGI29;CGI-29;MMRP19;dJ179L10.2 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 27kDa |
| Gene ID | 51074 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human APIP |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human APIP |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q96GX9 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria. |