Anti-ACKR2 Polyclonal Antibody
品牌：solarbio | 货号：K007999P
| 英文名称 | Anti-ACKR2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | D6;hD6;CCR9;CCBP2;CCR10;CMKBR9 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:30-150. |
| 交叉反应 | Human |
| 蛋白分子量 | 43kDa |
| Gene ID | 1238 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human ACKR2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human ACKR2 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | O00590 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. |