Anti-CTSC Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CTSC Polyclonal Antibody

品牌:solarbio | 货号:K007682P

英文名称 Anti-CTSC Polyclonal Antibody
宿主 Rabbit
别名 JP;HMS;JPD;PLS;CPPI;DPP1;DPPI;PALS;DPP-I;PDON1
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human
蛋白分子量 52kDa
Gene ID 1075
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CTSC
性状 液体
Public Immunogen Range A synthetic peptide of human CTSC
Subcellular Locations Cytoplasm
Swiss Prot P53634
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.