Anti-CRH Polyclonal Antibody
品牌:solarbio | 货号:K007404P
英文名称 |
Anti-CRH Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CRF |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:25-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
21kDa |
Gene ID |
1392 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CRH |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CRH |
Subcellular Locations |
Cytoplasm Nucleus |
Swiss Prot |
P06850 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. |