Anti-TPX2 Polyclonal Antibody
品牌:solarbio | 货号:K007208P
英文名称 |
Anti-TPX2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
DIL2;p100;DIL-2;HCTP4;FLS353;HCA519;REPP86;C20orf1;C20orf2;GD:C20orf1 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
86kDa |
Gene ID |
22974 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human TPX2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human TPX2 |
Subcellular Locations |
Cytoplasm Cytoskeleton Microtubule Nucleus |
Swiss Prot |
Q9ULW0 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2.? |