Anti-OPTN Polyclonal Antibody
品牌：solarbio | 货号：K007148P
| 英文名称 | Anti-OPTN Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NRP;FIP2;HIP7;HYPL;ALS12;GLC1E;TFIIIA-INTP |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 66kDa |
| Gene ID | 10133 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human OPTN |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human OPTN |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q96CV9 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. |