Anti-IMPDH2 Polyclonal Antibody
品牌：solarbio | 货号：K007078P
| 英文名称 | Anti-IMPDH2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IMPD2;IMPDH-II |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 56kDa |
| Gene ID | 3615 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human IMPDH2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human IMPDH2 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P12268 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5′-monophosphate into xanthine-5′-monophosphate, which is then converted into guanosine-5′-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. |