Anti-GSTA3 Polyclonal Antibody
品牌：solarbio | 货号：K007060P
| 英文名称 | Anti-GSTA3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | GTA3;GSTA3-3 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 25kDa |
| Gene ID | 2940 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GSTA3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human GSTA3 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q16772 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity.? |