Anti-CFL1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CFL1 Polyclonal Antibody

品牌:solarbio | 货号:K006993P

英文名称 Anti-CFL1 Polyclonal Antibody
宿主 Rabbit
别名 CFL
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量 19kDa
Gene ID 1072
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CFL1
性状 液体
Public Immunogen Range Recombinant protein of human CFL1
Subcellular Locations Cytoplasm Cytoskeleton Membrane Nucleus
Swiss Prot P23528
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.