Anti-SETD2 Polyclonal Antibody
品牌:solarbio | 货号:K006912P
英文名称 |
Anti-SETD2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
HYPB;SET2;HIF-1;HIP-1;KMT3A;HBP231;HSPC069;p231HBP |
应用 |
IHC |
稀释比例 |
IHC 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
288kDa |
Gene ID |
29072 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human SETD2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human SETD2 |
Subcellular Locations |
Nucleus |
Swiss Prot |
Q9BYW2 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Huntington’s disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. |