Anti-SETD2 Polyclonal Antibody
品牌：solarbio | 货号：K006912P
| 英文名称 | Anti-SETD2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HYPB;SET2;HIF-1;HIP-1;KMT3A;HBP231;HSPC069;p231HBP |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 288kDa |
| Gene ID | 29072 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SETD2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SETD2 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q9BYW2 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Huntington’s disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. |