Anti-SETD2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-SETD2 Polyclonal Antibody

品牌:solarbio | 货号:K006912P

英文名称 Anti-SETD2 Polyclonal Antibody
宿主 Rabbit
别名 HYPB;SET2;HIF-1;HIP-1;KMT3A;HBP231;HSPC069;p231HBP
应用 IHC
稀释比例 IHC 1:50-200.
交叉反应 Human Mouse
蛋白分子量 288kDa
Gene ID 29072
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human SETD2
性状 液体
Public Immunogen Range Recombinant protein of human SETD2
Subcellular Locations Nucleus
Swiss Prot Q9BYW2
克隆类型 Polyclonal Antibody
背景资料 Huntington’s disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.