Anti-DTX3 Polyclonal Antibody
品牌：solarbio | 货号：K006730P
| 英文名称 | Anti-DTX3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | RNF154 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 38kDa |
| Gene ID | 196403 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human DTX3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human DTX3 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q8N9I9 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | DTX3 functions as an E3 ubiquitin ligase. It is regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. |