Anti-NFKBID Polyclonal Antibody
品牌：solarbio | 货号：K006652P
| 英文名称 | Anti-NFKBID Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | TA-NFKBH;IkappaBNS |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:25-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 33kDa |
| Gene ID | 84807 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NFKBID |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NFKBID |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q8NI38 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine. |