Anti-SERPINB6 Polyclonal Antibody
品牌:solarbio | 货号:K006122P
英文名称 |
Anti-SERPINB6 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CAP;DFNB91;MSTP057;PI-6;PI6;PTI;SPI3 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human |
蛋白分子量 |
43kDa |
Gene ID |
5269 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human SERPINB6 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human SERPINB6 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P35237 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. |