Anti-ITGAE Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ITGAE Polyclonal Antibody

品牌:solarbio | 货号:K006117P

英文名称 Anti-ITGAE Polyclonal Antibody
宿主 Rabbit
别名 CD103;HUMINAE
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 130kDa
Gene ID 3682
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ITGAE
性状 液体
Public Immunogen Range Recombinant protein of human ITGAE
Subcellular Locations Membrane Single-pass type I membrane protein
Swiss Prot P38570
克隆类型 Polyclonal Antibody
背景资料 Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.