Anti-JARID2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-JARID2 Polyclonal Antibody

品牌:solarbio | 货号:K006069P

英文名称 Anti-JARID2 Polyclonal Antibody
宿主 Rabbit
别名 JMJ
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量 139kDa
Gene ID 3720
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human JARID2
性状 液体
Public Immunogen Range Recombinant protein of human JARID2
Subcellular Locations Nucleus
Swiss Prot Q92833
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.