Anti-PHOX2B Polyclonal Antibody
品牌：solarbio | 货号：K006047P
| 英文名称 | Anti-PHOX2B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NBLST2;NBPhox;PMX2B |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 32kDa |
| Gene ID | 8929 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PHOX2B |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PHOX2B |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q99453 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. |