Anti-GCDH Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-GCDH Polyclonal Antibody

品牌:solarbio | 货号:K005992P

英文名称 Anti-GCDH Polyclonal Antibody
宿主 Rabbit
别名 ACAD5;GCD
应用 WB
稀释比例 WB 1:200-2000.
交叉反应 Human Mouse Rat
蛋白分子量 48kDa
Gene ID 2639
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human GCDH
性状 液体
Public Immunogen Range Recombinant protein of human GCDH
Subcellular Locations Mitochondrion matrix
Swiss Prot Q92947
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12.