Anti-GCDH Polyclonal Antibody
品牌:solarbio | 货号:K005992P
英文名称 |
Anti-GCDH Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ACAD5;GCD |
应用 |
WB |
稀释比例 |
WB 1:200-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
48kDa |
Gene ID |
2639 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human GCDH |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human GCDH |
Subcellular Locations |
Mitochondrion matrix |
Swiss Prot |
Q92947 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. |