Anti-CYP46A1 Polyclonal Antibody
品牌:solarbio | 货号:K005923P
英文名称 |
Anti-CYP46A1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CP46;CYP46 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
57kDa |
Gene ID |
10858 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CYP46A1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CYP46A1 |
Subcellular Locations |
Endoplasmic reticulum membrane Microsome membrane Single-pass membrane protein |
Swiss Prot |
Q9Y6A2 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. |