Anti-CYP46A1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CYP46A1 Polyclonal Antibody

品牌:solarbio | 货号:K005923P

英文名称 Anti-CYP46A1 Polyclonal Antibody
宿主 Rabbit
别名 CP46;CYP46
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量 57kDa
Gene ID 10858
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CYP46A1
性状 液体
Public Immunogen Range Recombinant protein of human CYP46A1
Subcellular Locations Endoplasmic reticulum membrane Microsome membrane Single-pass membrane protein
Swiss Prot Q9Y6A2
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.