Anti-CAD Polyclonal Antibody
品牌：solarbio | 货号：K005771P
| 英文名称 | Anti-CAD Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CDG1Z;EIEE50;GATD4 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 243kDa |
| Gene ID | 790 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CAD |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CAD |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P27708 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. |