Anti-BMP6 Polyclonal Antibody
品牌:solarbio | 货号:K005765P
英文名称 |
Anti-BMP6 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
VGR;VGR1 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
57kDa |
Gene ID |
654 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human BMP6 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human BMP6 |
Subcellular Locations |
Secreted |
Swiss Prot |
P22004 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. |