Anti-CCR8 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CCR8 Polyclonal Antibody

品牌:solarbio | 货号:K005633P

英文名称 Anti-CCR8 Polyclonal Antibody
宿主 Rabbit
别名 CC-CKR-8;CCR-8;CDw198;CKRL1;CMKBR8;CMKBRL2;CY6;GPRCY6;TER1
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量 41kDa
Gene ID 1237
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CCR8
性状 液体
Public Immunogen Range Recombinant protein of human CCR8
Subcellular Locations Cell membrane Multi-pass membrane protein
Swiss Prot P51685
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.