Anti-FANCA Polyclonal Antibody
品牌：solarbio | 货号：K005384P
| 英文名称 | Anti-FANCA Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | FA;FA-H;FA1;FAA;FACA;FAH;FANCH |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 163kDa |
| Gene ID | 2175 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human FANCA |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human FANCA |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | O15360 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. |