Anti-DNAJC2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-DNAJC2 Polyclonal Antibody

品牌:solarbio | 货号:K003832P

英文名称 Anti-DNAJC2 Polyclonal Antibody
宿主 Rabbit
别名 MPHOSPH11;MPP11;ZRF1;ZUO1
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量 72kDa
Gene ID 27000
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human DNAJC2
性状 液体
Public Immunogen Range Recombinant protein of human DNAJC2
Subcellular Locations Cytoplasm Nucleus cytosol
Swiss Prot Q99543
克隆类型 Polyclonal Antibody
背景资料 This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.