Anti-DNAJC2 Polyclonal Antibody
品牌:solarbio | 货号:K003832P
英文名称 |
Anti-DNAJC2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
MPHOSPH11;MPP11;ZRF1;ZUO1 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
72kDa |
Gene ID |
27000 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human DNAJC2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human DNAJC2 |
Subcellular Locations |
Cytoplasm Nucleus cytosol |
Swiss Prot |
Q99543 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. |