Anti-UBE4A Polyclonal Antibody
品牌:solarbio | 货号:K003658P
英文名称 |
Anti-UBE4A Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
E4;UBOX2;UFD2 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
123kDa |
Gene ID |
9354 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human UBE4A |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human UBE4A |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q14139 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn’s disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |